Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk
نویسندگان
چکیده
منابع مشابه
Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk.
Recent debate has concentrated on the contribution of bad luck to cancer development. The tight correlation between the number of tissue-specific stem cell divisions and cancer risk of the same tissue suggests that bad luck has an important role to play in tumor development, but the full extent of this contribution remains an open question. Improved understanding of the interplay between extrin...
متن کاملTitle : Mathematical modeling links pregnancy - associated changes and breast cancer risk
Authors: Daniel Temko, Yu-Kang Cheng, Kornelia Polyak* and Franziska Michor* Authors’ Affiliations: Department of Biostatistics and Computational Biology, DanaFarber Cancer Institute, and Department of Biostatistics, Harvard T. H. Chan of Public Health, Boston, MA, USA. Centre for Mathematics and Physics in the Life Sciences and Experimental Biology (CoMPLEX), University College London, London,...
متن کاملPregnancy-Associated Breast Cancer
The incidence of pregnancy associated with breast cancer can be expected to increase as maternal age at the time of pregnancy continues to increase. Women diagnosed with breast cancer during pregnancy have similar disease characteristics to age-matched controls. Surgical treatment may be performed as for the nonpregnant women. Radiotherapy and endocrine or antibody treatment should be postponed...
متن کاملPregnancy-associated breast cancer
Traditionally pregnancy-associated breast cancer (PABC) is defined as any breast carcinoma diagnosed during pregnancy or within the first year after delivery. PABC is a rare event, representing overall between 0.2-3.8% of all breast cancers. The incidence of PABC is about 1 in 3000 pregnancies. The physiological changes occurring in the breast during pregnancy may obscure the presence of a palp...
متن کاملPregnancy-associated breast cancer.
The frequency of pregnancy-associated breast cancer, a rare but serious occurrence, may increase in light of the secular trends for lower parity in general and for older age at first full-term delivery in particular Data on PABC in individuals who are at high risk for breast cancer are limited. A computerized search of Pubmed showed that the reported incidence of PABC is 1:3000 pregnancies; it ...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2017
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-16-2504